1) Person vs Person
2) Person vs Nature
3) Person vs Animal
4) Person vs God
5). Person vs No one
All plots boil down to a variation of one of these conflicts. There is nothing truly new, unique or earth shattering about any story idea you think of.
What is truly new, unique and maybe even earth shattering is the way you tell the story. There is no duplicating your perspective, your style, your sensibilities because they are based in things that only you have gone through. Nobody can ever do it like you.
The only problem now is you have to do it. And do it in a way that is truly honest to you.